| Item Type | Name |
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Concept
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Alpha Particles
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Concept
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Tumor Necrosis Factor-alpha
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Concept
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Interferon-alpha
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Concept
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Hypoxia-Inducible Factor 1, alpha Subunit
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Concept
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Receptor, Interferon alpha-beta
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Concept
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Interleukin-2 Receptor alpha Subunit
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Concept
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Transforming Growth Factor alpha
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Concept
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Estrogen Receptor alpha
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Academic Article
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Cisplatin, fluorouracil, and leucovorin augmented by interferon alfa-2b in head and neck cancer: a clinical and pharmacologic analysis.
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Academic Article
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Phase I dose-escalation study of tumor necrosis factor-alpha and concomitant radiation therapy.
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Academic Article
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Tumor necrosis factor alpha (TNF-alpha) gene therapy targeted by ionizing radiation selectively damages tumor vasculature.
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Academic Article
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Differential retention of tumor- and differentiation-suppressor functions in cells derived from a human squamous cell carcinoma.
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Academic Article
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Pharmacodynamics of fluorouracil-based induction chemotherapy in advanced head and neck cancer.
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Academic Article
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Modulation of apoptotic response of a radiation-resistant human carcinoma by Pseudomonas exotoxin-chimeric protein.
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Academic Article
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Induction chemotherapy followed by concurrent chemoradiation for advanced head and neck cancer: improved disease control and survival.
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Academic Article
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Increased injection number enhances adenoviral genetic radiotherapy.
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Academic Article
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Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage.
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Academic Article
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Thymidylate synthase expression and response to neoadjuvant chemotherapy in patients with advanced head and neck cancer.
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Academic Article
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Concomitant chemoradiotherapy as primary therapy for locoregionally advanced head and neck cancer.
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Academic Article
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Radiation-inducible gene therapy.
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Academic Article
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Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft.
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Academic Article
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Molecular targeting of gene therapy and radiotherapy.
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Academic Article
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TNFerade Biologic: preclinical toxicology of a novel adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene.
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Academic Article
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Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine.
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Academic Article
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Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma.
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Academic Article
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Clinical protocol. An open-label, phase I, dose-escalation study of tumor necrosis factor-alpha (TNFerade Biologic) gene transfer with radiation therapy for locally advanced, recurrent, or metastatic solid tumors.
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Academic Article
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Selective gene expression using a DF3/MUC1 promoter in a human esophageal adenocarcinoma model.
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Academic Article
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Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes.
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Academic Article
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Transcriptional control of viral gene therapy by cisplatin.
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Academic Article
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Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation.
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Academic Article
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Control of gene therapy by MDR1 and EGR1 promoter sequences in transcriptional targeting by chemotherapy (Review).
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Academic Article
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Radiation-induced tumour necrosis factor-alpha expression: clinical application of transcriptional and physical targeting of gene therapy.
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Academic Article
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Radiation therapy: activation for gene transcription and the development of genetic radiotherapy-therapeutic strategies in oncology.
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Academic Article
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Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma.
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Academic Article
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Dual induction of the Epo-Egr-TNF-alpha- plasmid in hypoxic human colon adenocarcinoma produces tumor growth delay.
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Academic Article
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Induction chemotherapy followed by concomitant chemoradiotherapy in the treatment of locoregionally advanced nasopharyngeal cancer.
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Academic Article
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Chemoinducible gene therapy: a strategy to enhance doxorubicin antitumor activity.
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Academic Article
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Ionizing radiation: a genetic switch for cancer therapy.
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Academic Article
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Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy.
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Academic Article
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Diverse TNFalpha-induced death pathways are enhanced by inhibition of NF-kappaB.
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Academic Article
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Modeling of dose to tumor and normal tissue from intraperitoneal radioimmunotherapy with alpha and beta emitters.
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Academic Article
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TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors.
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Academic Article
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A Phase I trial of TNFerade biologic in patients with soft tissue sarcoma in the extremities.
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Academic Article
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Translation of the radio- and chemo-inducible TNFerade vector to the treatment of human cancers.
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Academic Article
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The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity.
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Academic Article
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Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy.
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Academic Article
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MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment.
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Academic Article
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SOD2-mediated adaptive responses induced by low-dose ionizing radiation via TNF signaling and amifostine.
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Academic Article
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Blockade of tumor necrosis factor alpha signaling in tumor-associated macrophages as a radiosensitizing strategy.
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Academic Article
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Ad.Egr-TNF and local ionizing radiation suppress metastases by interferon-beta-dependent activation of antigen-specific CD8+ T cells.
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Academic Article
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Clonal interactions in a human squamous cell carcinoma.
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Academic Article
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Gene therapy targeted by radiation preferentially radiosensitizes tumor cells.
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Academic Article
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Local gene delivery of tumor necrosis factor alpha can impact primary tumor growth and metastases through a host-mediated response.
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Academic Article
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Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells.
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Academic Article
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Membrane-derived second messenger regulates x-ray-mediated tumor necrosis factor alpha gene induction.
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Academic Article
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Resveratrol is an effective inducer of CArG-driven TNF-alpha gene therapy.
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Academic Article
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Spatial and temporal control of gene therapy using ionizing radiation.
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Academic Article
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Ketoconazole attenuates radiation-induction of tumor necrosis factor.
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Academic Article
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Cooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cells.
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Academic Article
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Tumor endothelial inflammation predicts clinical outcome in diverse human cancers.
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Academic Article
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The effect of the alpha-emitting radionuclide lead-212 on human ovarian carcinoma: a potential new form of therapy.
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Academic Article
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Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor alpha, and ceramide.
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Academic Article
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Radiation tolerance and the new biology: growth factor involvement in radiation injury to the lung.
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Academic Article
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Tumor necrosis factor-alpha-based gene therapy enhances radiation cytotoxicity in human prostate cancer.
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Academic Article
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Induction chemotherapy followed by concomitant chemoradiotherapy in the treatment of locoregionally advanced oropharyngeal cancer.
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Academic Article
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Tumor production of angiostatin is enhanced after exposure to TNF-alpha.
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Academic Article
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Regulation of tumor necrosis factor gene expression by ionizing radiation in human myeloid leukemia cells and peripheral blood monocytes.
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Academic Article
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Estimates of dose to intraperitoneal micrometastases from alpha and beta emitters in radioimmunotherapy.
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Academic Article
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The interaction between recombinant human tumor necrosis factor and radiation in 13 human tumor cell lines.
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Academic Article
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Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation.
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Academic Article
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Genetic radiotherapy overcomes tumor resistance to cytotoxic agents.
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Academic Article
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Cholesterol metabolism and resistance to tamoxifen.
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Academic Article
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STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.
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Academic Article
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Systemic delivery of the tumor necrosis factor gene to tumors by a novel dual DNA-nanocomplex in a nanoparticle system.
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Academic Article
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The relationship between expression of PD-L1 and HIF-1a in glioma cells under hypoxia.
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